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Nature: Why do you just want to lie down when you get sick?

Submitted by bioglyco on Sat, 06/10/2023 - 07:57

When we feel uncomfortable, we tend to eat less, drink less, and exercise less. This is not unique to humans—most animals reduce these three behaviors when fighting infection.

Recently, a new study pinpoints clusters of neurons that control these responses (uncomfortable behavior). By provoking immune responses in mice, the researchers demonstrated that specific cell populations in the brainstem could effectively induce three suggestive uncomfortable behaviors. In addition, inhibition of these neurons attenuates each behavioral element of the uncomfortable response.

CD BioGlyco Released Characterization Service of Glycosylation in Protein Drugs

Submitted by bioglyco on Sat, 06/10/2023 - 07:48

CD BioGlyco, a leader in glycosylation characterization, recently developed a comprehensive glycoproteomics platform to provide its customers worldwide with the characterization of glycosylation in protein drugs.

Glycoproteins, such as glycosyltransferases, glycosidases, erythropoietin, and cytokines, make up the majority of biotherapeutic products. Although the drugs themselves are complicated, it is urgent to develop techniques to characterize glycosylation in order to better evaluate their effects.

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