[Fildena 100 mg](https://snowmeds.com/product/fildena-100-mg-purple)
works by helping men with erectile dysfunction (ED) achieve and maintain an erection. The active ingredient in Fildena 100 mg is Sildenafil Citrate, which belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors.
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Mechanism of Action
Relaxation of Blood Vessels:
After sexual stimulation, the body releases nitric oxide (NO) in the penile tissue. Nitric oxide activates an enzyme called guanylate cyclase, which increases the levels of cyclic guanosine monophosphate (cGMP).
cGMP causes the smooth muscles in the blood vessels of the penis to relax. This relaxation allows the blood vessels to widen (dilate), increasing blood flow to the penis.
Inhibition of PDE5:
The enzyme PDE5 breaks down cGMP, leading to the end of an erection. Fildena 100 mg inhibits the PDE5 enzyme, which prevents the breakdown of cGMP.
By inhibiting PDE5, Fildena 100 mg allows cGMP to accumulate and persist longer, resulting in prolonged relaxation of the blood vessels and increased blood flow.
Erection During Sexual Stimulation:
The increased blood flow into the penis, combined with the restricted outflow due to the engorged erectile tissue, leads to an erection. However, sexual stimulation is necessary for Fildena 100 mg to work effectively.
Duration and Onset of Action
Onset: Fildena 100 mg typically starts working within 30 to 60 minutes after ingestion.
Duration: The effects can last up to 4-6 hours, allowing for an adequate time frame for sexual activity.
Summary
Fildena 100 mg facilitates erections by increasing blood flow to the penis through the inhibition of the PDE5 enzyme, thereby enhancing the body’s natural response to sexual stimulation. This makes it an effective treatment for men with erectile dysfunction.