Non-Invasive Bp optimizer Blood Pressure, Rat and Mouse Bp optimizer Measurement The NIBP methodology consists of utilizing a tail cuff placed on the tail to occlude the blood flow. Upon deflation, one of several types of NIBP sensors, placed distal to the occlusion cuff, can be utilized to monitor the rat BP. There are three (3) types of NIBP sensor technologies:, and Volume Pressure Recording. Each method will utilize an occlusion tail-cuff as part Leptitox of the procedure. 1.