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Modafinil is a medication that promotes wakefulness and is primarily used to treat conditions such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It is also sometimes prescribed off-label to treat conditions like attention deficit hyperactivity disorder (ADHD), depression, and fatigue associated with multiple sclerosis or fibromyalgia. Modafinil is known as a eugeroic or wakefulness-promoting agent. It works by increasing the levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine, which play roles in wakefulness and alertness. Modafinil is FDA-approved for the treatment of narcolepsy, a neurological disorder characterized by excessive daytime sleepiness, sudden episodes of muscle weakness (cataplexy), hallucinations, and sleep paralysis. It helps individuals with narcolepsy stay awake and alert during the day.

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