Market Overview: In 2021, the global market size for Real-Time Polymerase Chain Reaction (qPCR) reached USD 4.64 Billion, and a steady revenue Compound Annual Growth Rate (CAGR) of 7.8% is anticipated during the forecast period. The primary drivers of market growth include the increasing prevalence of chronic diseases like Human Immunodeficiency Virus (HIV), malaria, hepatitis, and cancer, coupled with notable technological advancements in qPCR devices.
The World Health Organization (WHO) reported approximately 10 million deaths in 2020, with cancer ranking among the leading causes worldwide, specifically breast cancer, expected to have 290,560 new cases in the U.S. in 2022.
Technological Advancements: Real-Time Polymerase Chain Reaction (qPCR) is a molecular biology technique used for monitoring PCR reactions in real-time, also known as quantitative PCR. Recent advancements in qPCR devices, exemplified by the release of New England Biolabs' LyoPrime Luna Probe One-Step RT-qPCR Mix, showcase improved stability at room temperature and robust performance.
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Market Dynamics: Drivers:
1. Increasing Focus on Food Safety: Stringent food safety standards globally, along with a growing emphasis on food security, drive the need for bacterial contamination detection. qPCR methods are crucial for identifying DNA segments in samples, enhancing sensitivity, diversity, multiplexing, and offering advantages over conventional food studies.
2. Rising Incidence of Chronic Diseases: The prevalence of diseases like cancer, malaria, and HIV fuels the demand for qPCR applications. The technique addresses limitations of conventional methods in terms of sensitivity, analyte diversity, cost, and turnaround time.
Restraints:
1. Inconsistent Results: Despite being viewed as a precise method, qPCR faces challenges such as inconsistent false positives and negatives. Technical limitations, including RNA quality, primer design, and nucleotide count, may impact experiment efficiency and yield.
Key Takeaways: Product Type Outlook:
1. Reagents and Consumables: Expected to dominate the market revenue share, these are essential for diagnosing diseases, ensuring specificity, and achieving sensitivity in qPCR.
2. Instruments: Anticipated to grow moderately, driven by the increasing demand for technologically advanced products, such as the Mic qPCR system.
3. Software and Services: Projected to grow steadily, aided by real-time PCR software facilitating data analysis, exemplified by Bio-Rad Laboratories' CFX Opus 96 and CFX Opus 384 Real-Time PCR Systems.
Application Outlook:
1. Blood and Oncology Testing: Largest revenue share in 2021, driven by the increasing cases of cancer and chronic diseases globally.
2. Pathogen Testing: Moderately contributing to revenue, with qPCR assays becoming more versatile for identifying various microorganisms.
3. Research and Development (R&D): Moderate revenue share, with qPCR assays being crucial for gene copy number determination and drug target development.
End-Use Outlook:
1. Hospitals: Largest revenue share in 2021, attributed to increased hospital admissions and regular testing for chronic diseases.
2. Diagnostic Centers: Moderate revenue share, driven by the availability of qPCR reagents for clinical diagnostic applications.
3. Pharma and Biotech Companies: Moderate revenue share, with companies conducting tests for microbial contamination using qPCR.
Regional Outlook:
1. North America: Largest revenue share in 2021, driven by significant technological advancements, regulatory support, and novel product introductions.
2. Europe: Moderate revenue growth rate, fueled by the incidence of genetic and infectious diseases, with the UK accounting for the largest regional share.
3. Asia Pacific: Steady revenue share, with increasing investments in scientific research and government initiatives to lower cancer incidence.
Competitive Landscape: The global qPCR market is moderately consolidated, with major companies like Abbott, Bio-Rad Laboratories, Thermo Fisher Scientific, and others engaging in product development and strategic alliances to expand their portfolios.
Recent Developments:
• Transgen Biotech launched a Monkeypox Virus (MPXV) Nucleic Acid qPCR Detection Kit.
• Cipla Inc. and Genes2Me Pvt. Ltd. collaborated to launch the "RT-Direct" multiplex COVID-19 RT PCR Test kit in India.
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