Market Overview: The global market size for organs-on-chips reached USD 24.4 million in 2020 and is projected to grow at a compound annual growth rate (CAGR) of 36.5% throughout the forecast period. The market is primarily driven by the increasing demand for alternatives to animal testing and the need for early detection of drug toxicity.
Organs-on-Chips Synopsis: Organ-on-chip technology represents an advanced 3D in vitro microfabricated system consisting of multichannel microfluidic cell cultures. Leveraging microfluidics, this technology mimics the functionality of specific organ or tissue components. Substantial research has already resulted in the development of various microfluidic chips capable of simulating the functions of organs such as lungs, liver, heart, and gut. Additionally, multi-organ chips have facilitated the identification of adverse drug effects on different organs, thereby potentially reducing both the duration and cost of drug development by detecting possible failures at an early stage. These advantages are key drivers of the market's revenue growth.
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Market Drivers: Organs-on-chips technology offers several benefits, including low manufacturing costs, the ability to test a wide range of medicine dosages, and a three-dimensional structure compared to traditional petri dishes. These factors have led to increased adoption across various fields, thereby boosting market growth. Additionally, organs-on-chips devices can maintain the microenvironment of human cells, including temperature, oxygen levels, and pH, by replicating internal conditions within the chip. The use of microfluidics makes these devices innovative solutions for research, as they are portable, easy to use, and amenable to mass production. Other factors driving market growth include the emphasis on developing alternatives to animal testing, increased research funding for organ-on-chip technology, and growing partnerships between organ-on-chip manufacturers and pharmaceutical companies. The expanding applications of these devices in healthcare, particularly in drug screening and organ culture, are expected to further drive revenue growth.
Market Restraints: Factors constraining the revenue growth of the organs-on-chips market include the increasing cost of devices, limitations of substrate materials such as polydimethylsiloxane (PDMS), and challenges related to the quality of substrate materials used in fabrication. Moreover, the growing complexity of organ-on-chip models presents a potential limitation to market expansion.
Key Insights: Type Outlook: The organs-on-chips market is segmented into lung, liver, heart, kidney, accessories, and other organs-on-chips. The accessories segment is expected to dominate the market, driven by its ease of use and the ability of hepatic tissues to maintain metabolic activity similar to in vivo conditions.
Application Outlook: Segmentation by application includes drug discovery, physiological model development, and toxicology research. The drug discovery segment is anticipated to witness the highest revenue growth, driven by the rapid screening of samples and the ability to monitor drug effects on the body using organ-on-chip devices.
End User Outlook: Among end users, the academics and research institutes segment is expected to achieve the fastest revenue growth, supported by increasing funding for cancer research and the rise of contract research organizations specializing in various fields relevant to organ-on-chip technology.
Regional Outlook: North America is projected to hold the largest market share during the forecast period, attributed to the availability of diverse services and increasing toxicological testing in the region. Asia Pacific is expected to experience significant revenue growth, driven by rising disposable income, government funding for regenerative medicine research, and increasing investment in R&D activities.
Key Companies Profiled: Major companies in the market, including Mimetas, InSphero, Emulate, Ascendance Bio, TissUse, CN Bio, Kirkstall, SynVivo, HUREL, AxoSim, and Nortis, have adopted various growth strategies such as product launches, partnerships, and expansions to maintain their positions in the pharmaceutical sector.
Segmentation Details: The report provides detailed segmentation of the organs-on-chips market based on type, offering, application, end user, and region, forecasting revenue growth globally, regionally, and at the country level from 2018 to 2028.
Customization Scope: The report offers 10 hours of free customization and expert consultation, covering aspects such as company ranking, competitive landscape, growth factors, and trends, ensuring comprehensive insights tailored to specific requirements.
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