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Feline herpesvirus type 1 (FHV-1) can cause acute and highly contagious infectious diseases in cats, namely feline infectious rhinotracheitis. In 1958, FHV-1 was isolated and identified for the first time from kittens suffering from respiratory diseases in the United States by Crandell et al. Clinical manifestations include keratoconjunctivitis, upper respiratory tract infection and miscarriage, and upper respiratory tract infection is the main symptom. Cats of all ages can be affected, mainly affecting young cats, and the incidence rate can reach 100%.

Antibody, also called Immunoglobulin, is a large Y globulin secreted by Effector B cell which is used in identifying and neutralizing the outsiders like bacterial and virus. Antibody is only found in blood ,body fluid and cytomembrane’s surface of Vertebrate. In addition, antibody can identify one characteristics of specific outsiders. The specific outsider is antigen. Antibody is a symmetrical structure containing four Polypeptide chains.