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Tapentadol is a centrally acting analgesic medication used for the management of moderate to severe pain. It works by binding to mu-opioid receptors in the central nervous system and inhibiting the reuptake of norepinephrine. This dual mechanism of action distinguishes tapentadol from other opioids.

Tapentadol is commonly prescribed for conditions such as chronic back pain, neuropathic pain, and post-operative pain. It is available in both immediate-release and extended-release formulations.