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Modafinil is a medication primarily used to promote wakefulness in individuals with sleep disorders such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Here are the main uses of modafinil:
Narcolepsy: Modafinil is FDA-approved for the treatment of narcolepsy, a chronic neurological disorder characterized by excessive daytime sleepiness, sudden episodes of muscle weakness (cataplexy), sleep paralysis, and hallucinations upon falling asleep or waking up. Modafinil helps to improve wakefulness and reduce daytime sleepiness in individuals with narcolepsy.
Obstructive Sleep Apnea (OSA): Modafinil may be prescribed off-label for the treatment of obstructive sleep apnea, a sleep disorder characterized by repetitive episodes of partial or complete upper airway obstruction during sleep, leading to disrupted sleep patterns and excessive daytime sleepiness. Modafinil can help to alleviate daytime sleepiness and improve wakefulness in individuals with OSA, particularly when other treatments such as continuous positive airway pressure (CPAP) therapy are not fully effective.
Shift Work Sleep Disorder (SWSD): Modafinil is also used off-label for the treatment of shift work sleep disorder, a circadian rhythm sleep disorder characterized by insomnia and excessive sleepiness occurring as a result of working non-traditional shifts, such as night shifts or rotating shifts. Modafinil helps to promote wakefulness and improve alertness in individuals who need to stay awake and alert during irregular work hours.
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