Licensed facilitators are present during your psilocybin session to assist with any physical needs, help you relax, and provide emotional support - without direct or psychoanalyzable advice or analysis of what might occur during this altered state experience.
Recent research that compared psilocybin with an SSRI revealed it could just as effectively alleviate depression symptoms with less side effects and greater brain network integration in its group than an SSRI group.
Depression
Depression is one of the world's most prevalent and disabling mental illnesses, impacting 10 percent of US residents every year. Characterized by low mood and feelings of worthlessness or hopelessness, depression may lead to self-harming behavior or thoughts of suicide.
Psilocybin https://www.shroomsdirect.io/ has been found to significantly alleviate depression in multiple clinical trials. Unfortunately, some studies have demonstrated temporary effects that eventually fade away - potentially underestimating its true antidepressant power.
This double-blind trial with 59 participants who suffered from major depressive disorder was conducted as a double-blind trial, where half received standard antidepressant drugs such as Escitalopram while half received combination treatment using Psilocybin drug and psychotherapy. Researchers observed that those treated with the combination therapy showed reduced BDI scores two days post session than escitalopram users two months after taking treatment; and these improvements continued over six months of therapy sessions. These remarkable results of this research demonstrate the power of Psilocybin to produce powerful antidepressant effects more rapidly and within just few sessions of therapy sessions! This research shows that conventional antidepressant drugs lack antidepressant effects that are needed; its antidepressant effects cannot match, producing optimal results more quickly!
Anxiety
Psilocybin can help people suffering from both depression and other forms of emotional trauma, including anxiety and hopelessness. Studies conducted between 2016 and 2020 indicate this. For instance, studies reported reduced feelings of hopelessness and anxiety among terminal cancer patients taking psilocybin. And another smaller 2020 study demonstrated its efficacy for treating treatment-resistant depression by significantly reducing anxiety symptoms like stress and depressiveness symptoms in this group of participants.
The study examined changes to functional brain networks EN and SN during fMRI scans, using measures known as network modularity as an indicator. Modularity decreases were more prominent among participants who received psilocybin than those receiving escitalopram; their decrease was strongly correlated with improvements to BDI score improvement at primary 6-week endpoint for the former group.
However, there was one caveat to take note of: the psilocybin-psilocin drug combination isn't without side effects. About 15% of participants experienced nausea or vomiting after taking higher doses, and half experienced psychological discomfort such as anxiety and paranoia - though these unpleasant experiences should be safe and brief if conducted in an appropriately managed setting, says Sackett.
Obsessive Compulsive Disorder
Psilocybin can help those living with OCD manage their obsessions and compulsions through repeated action taken to alleviate anxiety or the feelings it brings up, often ritualistic in nature and following specific patterns. Obsessions refer to thoughts that come back into your head repeatedly leading to anxiety, fear or guilt while compulsions involve performing actions repetitively to reduce anxiety or alleviate an obsessive thought - these can often become repetitive thoughts which repeat over and over.
Studies have also demonstrated the ability of psilocybin to promote brain network connectivity and alleviate depression symptoms. A recent randomized controlled trial comparing this psychedelic drug with an established selective serotonin reuptake inhibitor (SSRI), showed it worked just as effectively but with far fewer side effects.
Psilocybin is administered under the guidance of a trained therapist during an in-person, relaxing session that typically lasts about an hour. Typically, music or soothing sounds play while their eyes are covered; then the patient begins experiencing images, sounds and voices created by the psilocybin; their therapist will guide them through this experience while listening as the patient describes what they're experiencing.
Schizophrenia
Many individuals living with schizophrenia struggle to find appropriate treatments, leading to poor life outcomes - including shorter lifespans compared to people without schizophrenia.
Psilocybin can provide relief for some of the more debilitating symptoms of schizophrenia, such as hallucinations (seeing or hearing things that don't exist) and disorganized thinking. Furthermore, it may help those living with schizophrenia develop more effective coping mechanisms and decrease their need for medications.
Psychedelic drugs have the power to induce neurons to generate dendrites resembling tree branches and increase connections among them, improving communication among brain cells while decreasing anxiety and depression.
Studies by Carhart-Harris et al discovered that people with schizophrenia who took one dose of psilocybin experienced an 8-point improvement on the MADRS when compared with taking SSRIs, while Goodwin et al discovered that those receiving 25 mg of psilocybin experienced 50% greater improvement at three weeks than those taking 1 mg doses (or even none at all!).