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It was found out that naltrexone and bupropion combined, which might be marketed in the future as Contrave, give better weight loss results than diet and exercise alone.
Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err on the side of caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on the medications.
Researchers found that participants using this drug for the year, dropped a few pounds within 4 weeks and have kept the load off throughout the 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of several active ingredient, which can make them far better and safer.
Combo-pilling will be the newest fad or even better the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that since right now there are no long term prescription slimming capsules that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA.
Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug can also raise blood pressure level and pulse rate, and mustn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise blood pressure levels and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.
Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone can cause instant withdrawal. When suboxone is used correctly, the naloxone is destroyed in the liver soon after uptake in the intestines and it has no therapeutic effect. Buprenorphine will be the active substance; it really is absorbed beneath the tongue (and during the entire mouth) but destroyed with the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation once the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I also have treated addicts who may have had gastric bypass, the location where the first the main intestine is bypassed along with the stomach contents empty in a more distal part of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy the location where the drug is taken up through the duodenum and transferred directly to the liver through the portal vein, where it can be quickly and completely destroyed. After gastric bypass naloxone can be taken up by portions of the intestine that are not served with the portal system, causing blood levels of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.