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    Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heartrate, and really should not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    From a psychiatric viewpoint, evidence implies that the ordinary neural mechanism for goal-directed behavior may be hijacked through the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).